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Preservative Free + Safe with Contacts

Heyedrate Clinical

Lubricating eye drops for temporary dry eye relief

Clinically backed eye drops deliver intensive hydration and long-lasting protection.

SIZE: 1 x 10ml Bottle
1 x 10ml Bottle
$24.95
3 x 10ml Bottles
$7 Off
$67.37 $74.85
1

Reviews for Heyedrate Clinical

  • 5 stars: 27 (68%)
  • 4 stars: 2 (5%)
  • 3 stars: 8 (20%)
  • 2 stars: 2 (5%)
  • 1 star: 1 (3%)
v
verle p.

The drops work well, and are cheaper or just as cheap as Systane drops.

A
Austin A.

I’ve been using drops for years and my doctor recommended this new one. I thought it was super silky and smooth. No blur or burn. Love it!

d
denise f.

The bottle is so stiff & hard to try & squeeze a single drop out while using 2 hands to aim for one eye then keep squeezing to add to my other eye.

r
regina m.

The product is great! However, please cancel any future shipments. I can't afford them. Please DO NOT CHARGE MY CARD ANYMORE! Thank you kindly.

R
Robert I.

The drops, themselves, work pretty well, to lubicate my dry eyes. The problem is that, half way through the bottle, it does not go back to its original round shape. It stays squeezed, in the middle and then falls on its side. It also becomes very difficult, if not impossible, to squeeze liquid out. I end up togging the bottle out, way before it is finished - a waste of good money. I also wish this came in small, portable vials.

A
Anonymous

Doesn’t last very long for dry eye

A
Anonymous

Product is just what I need. Great stuff.

E
Eric S.

Works great

A
Anonymous

Not bad at all

r
richard c.

So far so good haven’t had the eye drops in use just for the last few days.Tell me is this on automatic refills. Let me know.

A
Anonymous

I don't find them to be an improvement over the Systane I've been using.

A
Anonymous

Great

M
Marion R.

The medication itself works as expected, similar to other dry eye drops. However, the container and squeeze process are very difficult to manipulate for folks who have older fingers, as in an 88 year-old person. The more popular OTC products have containers that are much easier to manage. I will have to think long and hard before I re-order.

J
Joseph T.

Just started using, will give them a chance, so far, so good.

D
Diane

Hydrates extremely well. No irritation. Love that it's preservative free.

D
Donald

Works well.

A
Anonymous

For the money it’s no better than Systane.

B
Beverly

Extremely hydrating! works wonderfully thank you

R
Richard L.L.

I have found Hyedrate Clinical to be very helpful when my eyes feel dry and scratchy. One drop in each eye solves my problem for many hours and I really like that.

M
Mindy M.

I like it very much. It feels great. Easy to use. I will reorder when I get low.

S
Susan B.

Love them, eye are clear and feel smooth

K
Katharine C.

Lasts longer and works better than any other eyedrop I've used

D
Deborah R.

While my eyes are less red they itch more which is extremely uncomfortable. I don’t see this product any better than over the counter eye drops. Plus I was given three bottle and I am almost finished either first one. I know I will run out before three months. Very disappointed.

L
Laurie M.

Very satisfied

S
Steve S.

Works better than other artificial tear products I have purchased in the past. Am buying this product from now on!

B
Bridget F.

Drops are So SLOW coming out
Not sure if this product is right for me

D
Donna M.

Didn't work for my dry eyes.

D
Donna O.

just began using this product, it is comfortable & seems to help when I need a little extra help with my dry eyes.

K
Kathy S.

I’ve had them for two weeks. So gar so good. Almost as good as the ones that afe $430/month copay on Medicare.

D
David K.

It’s average. Not sure if it’s worth the money.

A
Anonymous

I've been very impressed with this product - much better than expected!

s
saundra h.

I really likemy heyefrate. It a little slow coming out of the bottle

Customers Also Purchased
Benefits

Feel the Difference in Dry Eye Relief

Next generation eye drops that deliver intensive hydration, long-lasting protection and relief in every blink.

Intensive hydration

Supports your eyes in moments of dryness and irritation with a clinically backed, patented formula.

Long-lasting Relief

Temporarily alleviates common dry eye symptoms like burning, dryness or blurry vision while staying on the eye longer than ordinary drops.

Adaptive Comfort

Designed to move with your eyes, Hylan‑A Adaptive Comfort Shield® technology adapts to every blink, helping each drop stay where it’s needed while delivering the feel and comfort of natural tears.

Ingredients

Formulated for Performance and Comfort

Adaptive Comfort

Not all eye drops are created equal. Many standard drops dissipate quickly after application—and with them, the relief they’re meant to provide.

Hylan-A Adaptive Comfort Shield® technology features a high-molecular-weight form of hyaluronic acid – the highest weight available in the U.S. – which allows it to remain on the eye’s surface longer and more closely match the feel of natural tears. Combined with the power of active ingredient, Povidone, it helps deliver longer-lasting comfort and a more satisfying drop experience.

Formulated for Safety

Heyedrate Clinical is preservative‑free and 3x filtered for ultimate purity and safety, so you can feel confident using it as part of your daily eye care routine.

Results

Results You Can See—and Feel

27%
decrease in daily eye drop frequency*
77%
of users experienced improvement in eye comfort and clarity**

* Medic, nika et al. “Application frequency - key indicator for the efficiency of severe dry eye disease treatment - evidence for the importance of molecular weight of hyaluronan in lubricating agents.” Acta ophthalmologica vol. 102,5 (2024): e663:e671. doi:10.1111/aos.16609. Mean daily dropping frequency at conclusion of week 8.

** van Setten, G.B., et al., The HYLAN M Study: Efficacy of 0.15% High Molecular Weight Hyaluronan Fluid in the Treatment of Severe Dry Eye Disease in a Multicenter Randomized Trial. J Clin Med, 2020. OSDI improvement at the end of week 8.

How it works

The Science Behind Healthy Tears

Your eyes rely on a healthy tear film to stay hydrated and comfortable. When you have poor quality or quantity of natural tears, you may experience red, irritated eyes or blurry vision. Heyedrate Clinical can supplement your natural tears and provide much needed relief.

  • What is Tear Film?

  • The Cause of Dry, Irritated Eyes

  • How Heyedrate Can Help

What is Tear Film?

Heyedrate Clinical Reviews

  • 5 stars: 27 (68%)
  • 4 stars: 2 (5%)
  • 3 stars: 8 (20%)
  • 2 stars: 2 (5%)
  • 1 star: 1 (3%)
v
verle p.

The drops work well, and are cheaper or just as cheap as Systane drops.

A
Austin A.

I’ve been using drops for years and my doctor recommended this new one. I thought it was super silky and smooth. No blur or burn. Love it!

d
denise f.

The bottle is so stiff & hard to try & squeeze a single drop out while using 2 hands to aim for one eye then keep squeezing to add to my other eye.

r
regina m.

The product is great! However, please cancel any future shipments. I can't afford them. Please DO NOT CHARGE MY CARD ANYMORE! Thank you kindly.

R
Robert I.

The drops, themselves, work pretty well, to lubicate my dry eyes. The problem is that, half way through the bottle, it does not go back to its original round shape. It stays squeezed, in the middle and then falls on its side. It also becomes very difficult, if not impossible, to squeeze liquid out. I end up togging the bottle out, way before it is finished - a waste of good money. I also wish this came in small, portable vials.

A
Anonymous

Doesn’t last very long for dry eye

A
Anonymous

Product is just what I need. Great stuff.

E
Eric S.

Works great

A
Anonymous

Not bad at all

r
richard c.

So far so good haven’t had the eye drops in use just for the last few days.Tell me is this on automatic refills. Let me know.

A
Anonymous

I don't find them to be an improvement over the Systane I've been using.

A
Anonymous

Great

M
Marion R.

The medication itself works as expected, similar to other dry eye drops. However, the container and squeeze process are very difficult to manipulate for folks who have older fingers, as in an 88 year-old person. The more popular OTC products have containers that are much easier to manage. I will have to think long and hard before I re-order.

J
Joseph T.

Just started using, will give them a chance, so far, so good.

D
Diane

Hydrates extremely well. No irritation. Love that it's preservative free.

D
Donald

Works well.

A
Anonymous

For the money it’s no better than Systane.

B
Beverly

Extremely hydrating! works wonderfully thank you

R
Richard L.L.

I have found Hyedrate Clinical to be very helpful when my eyes feel dry and scratchy. One drop in each eye solves my problem for many hours and I really like that.

M
Mindy M.

I like it very much. It feels great. Easy to use. I will reorder when I get low.

S
Susan B.

Love them, eye are clear and feel smooth

K
Katharine C.

Lasts longer and works better than any other eyedrop I've used

D
Deborah R.

While my eyes are less red they itch more which is extremely uncomfortable. I don’t see this product any better than over the counter eye drops. Plus I was given three bottle and I am almost finished either first one. I know I will run out before three months. Very disappointed.

L
Laurie M.

Very satisfied

S
Steve S.

Works better than other artificial tear products I have purchased in the past. Am buying this product from now on!

B
Bridget F.

Drops are So SLOW coming out
Not sure if this product is right for me

D
Donna M.

Didn't work for my dry eyes.

D
Donna O.

just began using this product, it is comfortable & seems to help when I need a little extra help with my dry eyes.

K
Kathy S.

I’ve had them for two weeks. So gar so good. Almost as good as the ones that afe $430/month copay on Medicare.

D
David K.

It’s average. Not sure if it’s worth the money.

A
Anonymous

I've been very impressed with this product - much better than expected!

s
saundra h.

I really likemy heyefrate. It a little slow coming out of the bottle