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*Herman JP, Goudey SJK, Davis RL. Case report of dietary supplements improving macular pigment and visual function. Adv Ophthalmol Vis Syst. 2017;6(1):24-35. DOI: 10.15406/aovs.2017.06.00166


**Widomska J, SanGiovanni JP, Subczynski WK. Why is Zeaxanthin the Most Concentrated Xanthophyll in the Central Fovea? Nutrients. 2020 May 7;12(5):1333. doi: 10.3390/nu12051333. PMID: 32392888; PMCID: PMC7284714.


***Larry D. Lawson, Bronwyn G. Hughes, Absorption of eicosapentaenoic acid and docosahexaenoic acid from fish oil triacylglycerols or fish oil ethyl esters co-ingested with a high-fat meal, Biochemical and Biophysical Research Communications, Volume 156, Issue 2, 1988, Pages 960-963, ISSN 0006-291X, https://doi.org/10.1016/S0006-291X(88)80937-9.


****Widomska J, SanGiovanni JP, Subczynski WK. Why is Zeaxanthin the Most Concentrated Xanthophyll in the Central Fovea? Nutrients. 2020 May 7;12(5):1333. doi: 10.3390/nu12051333. PMID: 32392888; PMCID: PMC7284714.


*****Li B, George EW, Rognon GT, Gorusupudi A, Ranganathan A, Chang FY, Shi L, Frederick JM, Bernstein PS. Imaging lutein and zeaxanthin in the human retina with confocal resonance Raman microscopy. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12352-12358. doi: 10.1073/pnas.1922793117. Epub 2020 May 14. PMID: 32409609; PMCID: PMC7275724.

*Richer SP, Stiles W, Graham-Hoffman K, Levin M, Ruskin D, Wrobel J, Park DW, Thomas C. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. Optometry. 2011 Nov;82(11):667-680.e6. doi: 10.1016/j.optm.2011.08.008. PMID: 22027699.


**Sangiovanni JP, Agrón E, Meleth AD, Reed GF, Sperduto RD, Clemons TE, Chew EY; Age-Related Eye Disease Study Research Group. {omega}-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr. 2009 Dec;90(6):1601-7. doi: 10.3945/ajcn.2009.27594. Epub 2009 Oct 7. PMID: 19812176; PMCID: PMC2777471.


***Larry D. Lawson, Bronwyn G. Hughes, Absorption of eicosapentaenoic acid and docosahexaenoic acid from fish oil triacylglycerols or fish oil ethyl esters co-ingested with a high-fat meal, Biochemical and Biophysical Research Communications, Volume 156, Issue 2, 1988, Pages 960-963, ISSN 0006-291X, https://doi.org/10.1016/S0006-291X(88)80937-9.


****Widomska J, SanGiovanni JP, Subczynski WK. Why is Zeaxanthin the Most Concentrated Xanthophyll in the Central Fovea? Nutrients. 2020 May 7;12(5):1333. doi: 10.3390/nu12051333. PMID: 32392888; PMCID: PMC7284714.


*****Li B, George EW, Rognon GT, Gorusupudi A, Ranganathan A, Chang FY, Shi L, Frederick JM, Bernstein PS. Imaging lutein and zeaxanthin in the human retina with confocal resonance Raman microscopy. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12352-12358. doi: 10.1073/pnas.1922793117. Epub 2020 May 14. PMID: 32409609; PMCID: PMC7275724.

*Richer SP, Stiles W, Graham-Hoffman K, Levin M, Ruskin D, Wrobel J, Park DW, Thomas C. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. Optometry. 2011 Nov;82(11):667-680.e6. doi: 10.1016/j.optm.2011.08.008. PMID: 22027699.


**Herman JP, Kleiner-Goudey SJ, Davis RL (2017) Case Report of Dietary Supplements Improving Macular Pigment and Visual Function. Adv Ophthalmol Vis Syst 6(1): 00166. DOI: 10.15406/aovs.2017.06.00166


***Ma L, Dou HL, Huang YM, Lu XR, Xu XR, Qian F, Zou ZY, Pang HL, Dong PC, Xiao X, Wang X, Sun TT, Lin XM. Improvement of retinal function in early age-related macular degeneration after lutein and zeaxanthin supplementation: a randomized, double-masked, placebo-controlled trial. Am J Ophthalmol. 2012 Oct;154(4):625-634.e1. doi: 10.1016/j.ajo.2012.04.014. Epub 2012 Jul 25. PMID: 22835510.


****Widomska J, SanGiovanni JP, Subczynski WK. Why is Zeaxanthin the Most Concentrated Xanthophyll in the Central Fovea? Nutrients. 2020 May 7;12(5):1333. doi: 10.3390/nu12051333. PMID: 32392888; PMCID: PMC7284714.


*****Li B, George EW, Rognon GT, Gorusupudi A, Ranganathan A, Chang FY, Shi L, Frederick JM, Bernstein PS. Imaging lutein and zeaxanthin in the human retina with confocal resonance Raman microscopy. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12352-12358. doi: 10.1073/pnas.1922793117. Epub 2020 May 14. PMID: 32409609; PMCID: PMC7275724.

*Jones, Lyndon et al., TFOS DEWS III Management and Therapy Report, American Journal of Ophthalmology, Volume 0, Issue 0


**Smith et al., Investigational Study of 3:1 rTG Omega-3 Supplementation


***A. Epitropoulos, et al. Effect of Oral re-esterified Omega-3 Nutritional Supplementation on Dry Eyes. Cornea. 2016; 35:1185-1191.


****Larry D. Lawson, Bronwyn G. Hughes, Absorption of eicosapentaenoic acid and docosahexaenoic acid from fish oil triacylglycerols or fish oil ethyl esters co-ingested with a high-fat meal, Biochemical and Biophysical Research Communications, Volume 156, Issue 2, 1988, Pages 960-963, ISSN 0006-291X, https://doi.org/10.1016/S0006-291X(88)80937-9.

*Stroman, DW. Reduction in Bacterial Load Using Hypochlorous Acid Hygiene Solution on Ocular Skin; Clinical Ophthalmology 2017:11 1-8.


**Kern, J. R. (2019, May 2). Dry Eye Patients Report Improvement in Symptoms with Hypochlorous Acid Use Over 30 Days [Graph]. In Dry Eye Patients Report Improvement in Symptoms with Hypochlorous Acid Use Over 30 Days.


***Epstein A, Pang L, Najafi-Tagol K, Najafi R, Stroman DW, Debabov D. Comparison of Bacterial Lipase Activity in the Presence of Eye Lid Cleansers. Presented at ARVO 2015 in Denver, CO.

*Jarmuda, Stanislaw et al. Potential Role of Demodex mites and bacteria in the induction of rosacea. Journal of Medical Microbiology. 2012; 61;1504-1510. 3 Cheng Cornea Sept 2020; 4 IOVS June 2020


**Tighe Sean, et al, Terpinen-4-ol is the Most Active Ingredient of Tea Tree Oil to Kill Demodex Mites, Translational Vision Science and Technology, August 2013, Vol. 2, No. 7


***Zhu M, Cheng C, Yi H, Lin L, Wu K. Quantitative Analysis of the Bacteria in Blepharitis With Demodex Infestation. Front Microbiol. 2018 Jul 31;9:1719. doi: 10.3389/fmicb.2018.01719. PMID: 30108572; PMCID: PMC6079233.


****Evren Kemer Ö, Karaca EE, Özek D. Efficacy of cyclic therapy with terpinen-4-ol in Demodex blepharitis : Is treatment possible by considering Demodex's life cycle? Eur J Ophthalmol. 2021 May;31(3):1361-1366. doi: 10.1177/1120672120919085. Epub 2020 Apr 24. PMID: 32329361.

*Craig JP, et al., TFOS DEWS II Report Executive Summary, The Ocular Surface (2017), http://dx.doi.org/10.1016/ j.jtos.2017.08.003


**Jones, Lyndon et al., TFOS DEWS III Management and Therapy Report, American Journal of Ophthalmology, Volume 0, Issue 0

*van Setten GB, Baudouin C, Horwath-Winter J, Böhringer D, Stachs O, Toker E, Al-Zaaidi S, Benitez-Del-Castillo JM, Beck R, Al-Sheikh O, Seitz B, Barabino S, Reitsamer HA, Müller-Lierheim WGK. The HYLAN M Study: Efficacy of 0.15% High Molecular Weight Hyaluronan Fluid in the Treatment of Severe Dry Eye Disease in a Multicenter Randomized Trial. J Clin Med. 2020 Nov 2;9(11):3536. doi: 10.3390/jcm9113536. PMID: 33147751; PMCID: PMC7693312.


**Cristian Guarise, Laura Acquasaliente, Gianfranco Pasut, Mauro Pavan, Matteo Soato, Giacomo Garofolin, Riccardo Beninatto, Elena Giacomel, Eleonora Sartori, Devis Galesso; The role of high molecular weight hyaluronic acid in mucoadhesion on an ocular surface model, Journal of the Mechanical Behavior of Biomedical Materials, Volume 143, 2023, 105908, ISSN 1751-6161, https://doi.org/10.1016/j.jmbbm.2023.105908.


***Özkan G, Turhan SA, Toker E. Effect of high and low molecular weight sodium hyaluronic acid eye drops on corneal recovery after crosslinking in keratoconus patients. BMJ Open Ophthalmol. 2025 Mar 29;10(1):e001890. doi: 10.1136/bmjophth-2024-001890. PMID: 40157723; PMCID: PMC11956357.